Rusty was first diagnosed with heart murmur grade 3/6 in August of 2016 while traveling and seeing a vet for an unrelated health issue. We were told at the time that heart murmurs are common and that it was unlikely it would progress to anything more serious. In January 2018, Rusty suddenly and with no warning whatsoever started coughing repeatedly. After a quick visit to the ER, he was misdiagnosed with kennel cough and given antibiotics. Two days later with his cough getting much worse, he finally got imaged and was diagnosed with MVD Stage B2 and CHF. We were (once again) traveling at the time and were advised that he may not even survive the flight back home. He was immediately put on pimobendan and Lasix which made the cough go away. Once we did get back home, we were seen by a cardiologist who performed an echocardiogram and confirmed the heart murmur was a grade of 5/6 and he had severe regurgitation. Rusty was given only 9 to 12 months to live.
Keisha first presented a stage 2 murmur in April 2017. No treatment was recommended at the time. On 17th December 2017 she was given diagnosis of MVD with CHF and placed on furosemide and spironolactone. Her ultrasound showed very enlarged heart (size of a Doberman) and damaged mitral valve, ruptured chords. After several CHF episodes, surgical options were researched and Jasmine vets in Japan referred Keisha to Niek Beijerink at University of Sydney. Keisha had surgery at University of Sydney with Dr. Uechi on April 19, 2018. She had a complication with a blood clot in her forelimb on day 6 after surgery and some hard swelling at surgery site but otherwise recovered well. Currently Keisha’s blood clot has resolved although still limping, her surgery site is improving daily and she is still on Vetmedin and blood thinners. On May 4 her ultrasound showed decrease in heart size, and her parents are waiting to see whether medication can be reduced/eliminated.
In July 2014 a level 2 murmur was detected during a routine visit at UF prior to his third dental cleaning and an echocardiogram confirmed Mitral Valve Disease. His murmur progressed to level 5 and in September 2017 he developed an exercise intolerance. He was taken to his primary care vet and and an x-ray confirmed the worst - congestive heart failure. Dutch went on Lasix for the fluid in his lungs, enalapril and pimobendan. Dr. Swift confirmed not just the heart failure but that he had maybe 8-9 months to live and recommended MVR surgery with Dr. Uechi. Dutch had mitral valve repair surgery at Clinique Veterinaire Bozon on February 1, 2018.
Dutch is currently off all meds except Vetmedin to keep the heart beating strong as the disease enlarged and twisted it prior to surgery. His heart has decreased in size and the murmur reduced to grade 2 and very mild regurgitation.
Breed: Yorkshire Terrier Age: 10 years old Diagnosis: Stage C Surgery Date: January 29, 2018 Hometown: New York, NY Owner: LiLi L Cardiologist: Dr. George Kramer,ACVS Surgical Team: France, Drs. Masami Uechi, Sabine & Jean Hugues Bozon
ToTo is a 10 year old Yorkshire Terrier from New York, NY. ToTo had a totally clean bill of health until a low grade murmur was detected in July of 2016. X-rays and echocardiogram at the time did not conclude treatment, just a follow up one year later. During pre-check for teeth cleaning three weeks ago, March 2017, blood work came back with slightly elevated enzymes in the liver; and x-ray showed a much more enlarged heart than last summer. The vet was not comfortable with putting him under until another echo was done, which concluded he had progressed to a grade 4.
Sophie is a 9 year old Cavalier King Charles Spaniel from Washington Crossing, PA. Sophie was diagnosed with MVD in June 2012. It was only a grade 2 murmur and did not require any medication at that time. She was rechecked in March 2013 and the MVD had progressed. There was some regurgitation with minimal heart enlargement so she was put on 25 mg Enalapril 2 x per day. Slowly over the following years her heart continued to enlarge and the murmur became more pronounced. In 2016 she was put on Vetmedin and at the time of her pre-op testing her heart had actually reduced in size but the regurgitation had gotten much worse over the five year period and she was getting close to Stage C right before her surgery.
Breed: Shih-Poo Age: 8 years old Diagnosis: Stage B2 Hometown: Chicago, IL
Maddox was asymptomatic with severe Mitral regurgitation and moderate Tricuspid regurgitation. Six months prior to MVD diagnosis, Maddox had no heart murmur before suddenly having grade 5/6. She was prescribed Pimobendan and remained stable until surgery at JASMINE Veterinary Cardiovascular Medical Center. Her heart showed progressive enlargement during each follow-up echocardiogram leading up to surgery which later confirmed Mitral valve prolapse and ruptured chordae tendineae.
Maddox has significant improvement including reduced heart size, extremely mild Mitral regurgitation, and no Tricuspid regurgitation 4 months post-surgery. “Diagnostic Impressions: The evaluation demonstrates degenerative mitral valve disease with an excellent result from valve repair surgery. The disease is extremely well compensated at this time and medical therapy is not warranted.”
Breed: Maltese Age: 10 years old Diagnosis: Stage C Hometown: Orlando, FL
Zoey was originally diagnosed with a heart murmur at four years old and told it wasn't an issue and that the condition would be monitored. After an episode of gasping and coughing in July 2016, Zoey was taken to the vet and misdiagnosed twice with pneumonia and a mass on her lung. She would not have survived the surgery at the time, so Zoey's owners took her to a known ER vet who knew right away it was her heart. She was put on Lasix, put in an oxygen chamber, and referred to a cardiologist at the University of Florida. During the misdiagnosis, Zoey had gone into CHF and ruptured cords. She was given anywhere from 2 months to 2 years to live. Dr. Simon Swift, the Medical Director and Clinical Cardiologist at UF reviewed all of Zoey’s records and suggested that Zoey was a good candidate for mitral valve repair surgery and she was referred to Dr. Sabine in France.
Zoey is currently stable and on four medications in the morning and three at night. She gets acupuncture treatments twice a month and is on multiple supplements.. Zoey is still under the supervision of Dr. Swift and she is scheduled for surgery in France on September 22, 2017.
Cardiologist : Dr. Simon Swift, University of Florida Owner: Jeanette Jordan
Breed: Cavalier King Charles Spaniel Age: 8 years old Diagnosis: Stage D Hometown: Sevres, France
In March 2016, Easy was diagnosed with Mitral Valve Disease. She had an enlarged heart which stabilized with drug therapies. In August 2017, she suffered from pulmonary edema and progressed to stage D. After finding out about the surgery, Easy's parents met with Sabine Bozon urgently. She said that Easy had only a few days to live and agreed to make the surgery urgently after having treated the edema. The day before the operation, she discovered 2 blood clots and hospitalized her. Then the surgery on September 20th went well but Easy had 2 more clots one week after leaving the clinic that she evacuated with drugs. Currently, Easy is recovering at home and doing very well!
Breed: Chihuahua Age: 7 years old Diagnosis: Stage C Hometown: Albany, NY
Sachie was diagnosed with a heart murmur in April 2017. Then, in June 2017 she was confirmed to be in MVD Stage B2 with a murmur of 4/5. Between June and her surgery on September 20, 2017, Sachie progressed to Stage C but remained stable. Her surgery at the Bozon clinic in France was a success and Sachie seems to be doing very well. Her energy level has increased and she looks great.
Breed: Chihuahua/Yorkie Mix Age: 10 years old Diagnosis: Stage C Hometown: London, UK
Snoopy went to the vet to be diagnosed with MVD two months prior to surgery. He was in heart failure with a 6 out of 6 heart murmur. After a successful mitral valve repair on September 19th at the Bozon clinic in France, Snoopy is now at Stage B1 and doing very well. Dr. Bozon said that his heart is almost perfect. His regurgitation has significantly reduced but he still suffers from a cough.
Breed: Maltese Age: 11 years old Diagnosis: Stage B2/C Hometown: Pyeongtaek, South Korea
In November 2016, Mong was hospitalized with pulmonary edema and diagnosed with a chordae tendineae rupture and Mitral valve disease. Last summer, Mong's brother passed away so his parents want to save him more than anything. In Korea, there was no information on the valve operation but research on overseas sites revealed that the operation was available in Japan. Mong's owners immediately began the Japan quarantine process and during the waiting period, his heart condition has gotten worse causing arrhythmia and syncope. Mong is scheduled for surgery at JASMINE in Japan on August 7, 2017. We wish Mong a stable condition until his surgery.
Breed: Cavalier King Charles Spaniel Age: 10 years old Diagnosis: Stage B2/C Hometown: Long Island, NY
Bailey was diagnosed in October 2013 with Mitral Valve Disease Stage B2. He was taken to the cardiologist after his owner detected his murmur. On Valentine's Day 2015, Bailey went into mild CHF and in 2016, Bailey had several readings of pulmonary hypertension. Surgery is scheduled in Japan with Dr. Uechi for July 25, 2017. Bailey will be 11 years old at the time of his procedure. He gets regular acupuncture laser treatments and is on multiple supplements, including herbal therapy.
Breed: Chihuahua/Pekingese/Pomeranian Age: 10 years old Diagnosis: Stage B2 Hometown: San Francisco, CA
Paco was diagnosed with Mitral Valve Disease Stage B2 in October 2016. He is currently on pimobendan and enalapril, but no diuretics. Non-active at baseline, visits the dog park 1-2x/day, and takes short walks around the neighborhood or at the beach. Currently, he has no outward symptoms, other than a loud murmur. Paco is scheduled for surgery at the JASMINE clinic in Japan on July 24, 2017. We hope that Paco continues to be symptom free while he waits patiently for his big adventure.
Breed: Chihuahua/Yorkie Age: 8 years old Diagnosis: Stage B2/C Hometown: Palm Beach Garden, FL
Max was first adopted in October 2009 from a shelter and was so tiny his new owners had to fatten him up. It's a good thing he loves chicken! He loves playing with his Samoyed brother Kodi and loves his morning walks. He was first diagnosed with MVD Stage B1 in October 2015 and then Stage B2/C in January 2017. We look forward to Max's surgery at the Bozon Clinic in France on July 5th and stable prognosis until then.
Breed: Cavalier King Charles Spaniel Age: 8 years old Diagnosis: Stage D Hometown: New York/Florida
Daisy was diagnosed with a heart murmur level 3/6 in January 2016. She was not placed on meds until July of that year and was started on Vetmedin (Pimo). By June 2017 her mitral valve disease had progressed and was on Vetmedin, Enalapril, Hydrocodone, Spironolactone Digoxin & Furosemide and needing diapers. Daisy was hospitalized in June 2017 due to vomiting & dehydration, taken off Digoxin. Her BNP was elevated to 4500 and lost 4 lbs prior to surgery. Daisy was fit in as an emergency patient at Clinic Veterinaire Bozon on July 5, 2017. She is a fighter and wonderful success story. Currently, her murmur is reduced to a 3/6, is stable back in Stage B, and remains only on sildenaphil to help with the pressure that remains on her heart. No more diapers for Daisy!
Cardiologist : Dr. George Kramer, Atlantic Coast Veterinary Specialists Owner: Sharon & Roger Hawkins
Breed: Cavalier King Charles Spaniel Age: 9 years old Diagnosis: Stage C2 Hometown: Lake Forest, CA
Harper lives in Lake Forest, California (Orange County), with Kim and Jerry Thornton, whom she owns body and soul, another Cavalier named Keeper and a Chihuameranian named Gemma--the one who really rules the roost. She likes to do nose work--she competes at the NW3 level--but her main focus is trying to knock on the neighbors' doors to see if they have any treats for her. She was diagnosed with a murmur when she was 5 years old but did not become symptomatic until January of this year. She's scheduled for surgery on May 26 at the Bozon Clinic, after a few days in Paris first with mom and dad.
Breed: Cavalier King Charles Spaniel Age: 10 years old Diagnosis: Stage C Hometown: Woburn, MA
Chuck was diagnosed when he was 6 years old with a heart murmur but did not require medication to control symptoms until the fall of 2016 when he began coughing frequently. His X-Ray shows a very enlarged heart and is currently holding steady on medication until his surgery date of May 23, 2017. We wish Chuck good health until his surgery date and a fast recovery!
Breed: Japanese Chin Age: 8 years old Diagnosis: Stage B2 Hometown: Ft. Lauderdale, FL
Zeus was diagnosed at Stage B2 and has been noticeably slowing down and coughing more as the disease progresses. He had a very successful mitral valve repair surgery on March 24, 2017 at Clinique Veterinaire Bozon. After surgery, Zeus had some additional coughing from being intubated, but is currently recovering comfortably at home.
Breed: Cavalier King Charles Spaniel Age: 7-1/2 years old Diagnosis: Stage B2+ Hometown: Maple Valley, WA
In November 2016, Bentley was diagnosed with Mitral Valve Disease Stage B2+ when his heart murmur elevated to a Grade 4. He had an enlarged heart with severe regurgitation and was stabilized with drug therapies. One week prior to traveling to France for Mitral Valve Repair surgery, Bentley went into Congestive Heart Failure, Stage C. With an additional drug added, he was stabilized once again. Bentley received his surgery in Versailles, France on March 23, 2017. Bentley’s cardiologist, Dr. Mikaela Mueller, also flew to France to observe this miraculous surgery. Bentley had his 1-month post-op checkup on April 5, and is doing great! His heart is back to normal size, he is off of all drug therapies, and his regurgitation was reduced to a normal range.
Breed: Yorkshire Terrier Age: 11 years old Diagnosis: Stage C Hometown: Prague, Czech Republic
Bellissima, also called Belisa, was diagnosed in 2014 with a heart murmur which progressed to stage C in December 2016 prior to her surgery at the Bozon Clinic in Versailles, France on March 21, 2017. She had a successful mitral valve repair that day, and had many complications after surgery, some of which had nothing to do with her heart or the surgery. However, we are so happy to report that Belisa is back at home recovering comfortably.
Veterinarian: Dr. Vojtěch Novák Owner: Tomáš Kučera Read Belisa's surgery story here
Breed: Chihuahua Mix Age: 12 years old Diagnosis: Stage D+ Hometown: New York
Duke has had a known murmur since he was adopted and vets said from the beginning it would develop into heart failure. In November 2015, Duke was taken to the vet with labored breathing and was diagnosed with Congestive Heart Failure and had fluid on his lungs. For a year after, Duke was treated with holistic supplements and acupuncture as well as a substantial cocktail of medications prescribed by Dr. Kramer. In October 2016, he went into Stage D and was not responding well to any of his treatments. Duke had an emergency surgery at the Bozon Clinic on December 8, 2016 and was on the verge of complete heart rupture. Today, Duke is doing well. His heart, ventricle, and atrium have all reduced in size. He has no sign of infection, clots, or fluid in his lungs. He breathes, sleeps, and eats very well (all areas he was struggling with when sick with the disease). He is becoming more active and wants to run when he is taken out for walks.
Breed: Yorkipoo Age: 10 years old Diagnosis: Stage C Hometown: San Marcos, CA
Bodhi was diagnosed in the summer of 2015 in Phoenix, AZ with mitral valve disease and told nothing could be done except to medicate and given 1-2 years to live. Prior to surgery, Dr. Sabine Bozon diagnosed an advanced stage of mitral valve disease and saw that Bodhi's heart was close to rupture. Intervention was performed on December 7, 2016 at the Bozon Clinic in Versailles, France. Currently, Bodhi has some tracheal collapse which leaves him coughing at times but other than that he will be ready to run on the beach again once he is cleared for normal activity. Dr. Hodge evaluated Bodhi at his one month post-surgery check up and said his heart was back to a normal size and that his regurgitation level was at about 28% compared to over 80% at the time of surgery.
Breed: Maltipoo Age: 9 years old Diagnosis: Stage C Hometown: New York, NY
Tiffany was diagnosed on October 4, 2016 with stage C MVD. It was also suspected that she had numerous ruptured chordae tendineae. Her prognosis was poor. Her disease had a rapid onset and quick progression. At her prior check-up no murmur was even detected.
Tiffany had surgery with Dr. Uechi at the BOZON Clinic on December 6, 2016. As suspected, Tiffany had 5 ruptured chordae tendineae that were successfully replaced. Prior to surgery, Tiffany’s heart was extremely enlarged. It is now almost within the margins of normalcy, and her mitral valve regurgitation is minimal. She is also off all medication.
Breed: Coton de Tulear Age: 9 years old Diagnosis: Stage B2 Hometown: Vienna, VA
Levi was diagnosed in July during a routine checkup with a heart murmur that was not present a few months earlier. Cardiologists confirmed that the murmur was a result of Mitral Valve Disease and chord rupture with an enlarged heart, stage B1. Prior to surgery, Levi was assessed at stage B2, his heart condition somewhat stabilized with drug therapy between July and December. Levi had Mitral Valve Repair at the Bozon Clinic in Versailles, France on December 6, 2016. Levi had a great 3 month post-op checkup at CVCA and has been cleared for normal activity. His heart size has reduced to normal, is off of all drug therapies, and the regurgitation is reduced significantly.
Breed: Maltese Age: 5 years old Diagnosis: Stage B2 Hometown: Los Angeles, CA
Zoey was diagnosed in July of 2016 with a heart murmur and stage B2 of mitral valve disease with a very enlarged heart. She was stabilized with drug therapies until her surgery date which was October 26, 2016 at the Bozon Clinic in Versailles, France. Today, Zoey remains in stable condition and had a great checkup at her 3-month postoperative appointment. Her heart size and reduced regurgitation have remained steady since she left the clinic in France and is now cleared for normal puppy activity.
Breed: Cavalier King Charles Age: 8 years old Diagnosis: Stage D Hometown: Carlsbad, CA
Prudence was diagnosed with a heart murmur for the first time in June 2016. We immediately had a cardiologist perform an echocardiogram which revealed stage B2 mitral valve disease. Unfortunately, Prudence's MVD progressed rapidly and within 6 weeks was in congestive heart failure. At the time of her surgery on October 24, 2016 she was in refractory stage D (hospitalized). Prudence's MVD is now reduced to stage B1 (murmur: no enlargement). Her echocardiogram shows the mitral valve regurgitation is significantly reduced and her murmur is a grade 2.